^99mTc-labelled biphosphonates

Clinical Evaluation	Osteoblastic activity
Type of Imaging	Scintigraphy
Grade of Recommendation	B (generally recommended)
Level of Evidence	well-designed NM recommendations
Effective Dose	4.9 µSv/MBq
Bibliographic Reference	Lauer, I., Czech, N., Zieron, J., Sieg, P., Richter, E., Baehre, M. Assessment of the viability of microvascularized bone grafts after mandibular r... read more Lauer, I., Czech, N., Zieron, J., Sieg, P., Richter, E., Baehre, M. Assessment of the viability of microvascularized bone grafts after mandibular reconstruction by means of bone SPET and semiquantitative analysis. Eur J Nucl Med. 2000; https://doi.org/10.1007/s002590000334 Kim, H., Lee, K., Ha, S., Shin, E., Ahn, K. M., Lee, J. H., et al. Predicting Vascularized Bone Graft Viability Using 1-Week Postoperative Bone SPECT/CT After Maxillofacial Reconstructive Surgery. Nucl Med Mol Imaging. 2020; https://doi.org/10.1007/s13139-020-00670-7 Van den Wyngaert, T., Strobel, K., Kampen, W. U., Kuwert, T., van der Bruggen, W., Mohan, H. K., et al. The EANM practice guidelines for bone scintigraphy. Eur J Nucl Med Mol Imaging. 2016; https://doi.org/10.1007/s00259-016-3415-4 read less

Clinical Evaluation
Osteoblastic activity
Type of Imaging
Scintigraphy
Grade of Recommendation
B (generally recommended)
Level of Evidence
well-designed NM recommendations
Effective Dose
4.9 µSv/MBq
Bibliographic Reference
Lauer, I., Czech, N., Zieron, J., Sieg, P., Richter, E., Baehre, M. Assessment of the viability of microvascularized bone grafts after mandibular r... read more Lauer, I., Czech, N., Zieron, J., Sieg, P., Richter, E., Baehre, M. Assessment of the viability of microvascularized bone grafts after mandibular reconstruction by means of bone SPET and semiquantitative analysis. Eur J Nucl Med. 2000; https://doi.org/10.1007/s002590000334 Kim, H., Lee, K., Ha, S., Shin, E., Ahn, K. M., Lee, J. H., et al. Predicting Vascularized Bone Graft Viability Using 1-Week Postoperative Bone SPECT/CT After Maxillofacial Reconstructive Surgery. Nucl Med Mol Imaging. 2020; https://doi.org/10.1007/s13139-020-00670-7 Van den Wyngaert, T., Strobel, K., Kampen, W. U., Kuwert, T., van der Bruggen, W., Mohan, H. K., et al. The EANM practice guidelines for bone scintigraphy. Eur J Nucl Med Mol Imaging. 2016; https://doi.org/10.1007/s00259-016-3415-4 read less